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Drugs that have been documented to cause problems in collies include:

 

Acepromazine
Butorphanol
Emodepside

Erythromycin

Vincristine Vinblastine Doxorubicin

Ivermectin,  Heartguard

Loperamide – (Imodium) At doses used to treat diarrhea.

Selamectin, milbemycin, and moxidectin (antiparasitic agents) 

Spinosad, a flea-control medication included in 

     Comfortis

     Trifexis

     Vethical AcuGuard and ComboGuard

     Nexgard

     Bravecto

     Revolution  

 

~HEARTWORM PILLS~

Please only give your collie: Interceptor® Plus‎, Interceptor, or Sentinel. This is so important, because many veterinarians have been telling collie buyers there is only a small amount of ivermectin or spinosad (flea med) in heartworm pills that it should be quite safe. This is not the case! There can be a toxic reaction that allows the ivermectin to pass the dog's blood-brain barrier and into its central nervous system, which can be lethal for the animal.

Symptoms for the dog may be acute or mild. Acute signs will become apparent within 4 to 12 hours of the drug's administration. In mild cases, symptoms will occur between 48 to 96 hours after your dog has been treated. Such symptoms include: 

 

• Lethargy

• Depression

• Drooling

• Vomiting

• Dilation of the pupil

• Loss of appetite (anorexia)

• Difficulty controlling voluntary movement

• Disorientation

• Tremors/Seizures

• Inability to stand

• Blindness

• Slow heartbeat

• Respiratory distress

• Coma